3-(4-CHLOROPHENYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID - Names and Identifiers
3-(4-CHLOROPHENYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID - Physico-chemical Properties
Molecular Formula | C11H9ClN2O2
|
Molar Mass | 236.65 |
Density | 1.38±0.1 g/cm3(Predicted) |
Boling Point | 443.7±35.0 °C(Predicted) |
pKa | 2.87±0.25(Predicted) |
Storage Condition | 2-8°C |
Sensitive | Irritant |
MDL | MFCD08446011 |
3-(4-CHLOROPHENYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | 22 - Harmful if swallowed
|
Hazard Class | IRRITANT |
3-(4-CHLOROPHENYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID - Introduction
5-(4-ChlO-ORPHENYL)-ACID is an organic compound with the chemical formula C11H8ClN3O2. It has the following properties:
1. Appearance: colorless to yellowish crystalline solid
2. melting point: 180-184 ℃
3. Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide, dichloromethane, etc.
4. Stability: relatively stable at room temperature
The main uses of this compound include:
1. Intermediate: It can be used as an intermediate for the synthesis of other organic compounds, for the preparation of drugs, dyes and pesticides.
2. Research: It is used in the field of scientific research, such as pharmaceutical research and organic synthesis.
The method for preparing 5-(4-Chloro-phenyl)-Cr acid is as follows:
1. First, benzoic acid and benzene ring addition agent are reacted to generate phenyl ketone.
2. Next, a reductive coupling reaction of phenyl ketone and phenyl boronic ester with a Pd-C catalyst generates the corresponding acid.
3. By adjusting the reaction conditions, the target product 5-(4-Chloro-phenyl)-acid can be generated.
Regarding safety information, 5-(4-Chloro-phenyl)-acid should be stored in a place protected from light, moisture and good ventilation, and away from fire and high temperature. Appropriate protective equipment, such as chemical safety glasses, gloves and lab clothes, should be worn during operation. In addition, the relevant safety procedures should be followed to avoid direct contact and inhalation of the compound. In the event of an accident, appropriate first aid measures should be taken immediately.
Last Update:2024-04-09 21:01:54